BOSTON, MA
September 1, 2025
Rishab Jain today announced the launch of Claisen, an AI-driven GI health startup focused on practical, at-home care for heartburn/GERD, bloating and gas. Claisen pairs a short, clinician-informed intake with step-wise routines and right-sized product kits—so people can stop guessing and start following a plan that fits real life.

Rishab Jain is a Harvard neuroscience student and technologist, founder & CEO of Claisen, with prior award-winning work applying machine learning to pancreatic radiotherapy and codon-optimisation for recombinant vaccines (ICOR). Rishab Jain is best known for early work applying machine learning to difficult clinical problems and was awarded America's Top Young Scientist and was featured by TIME Magazine as TIME’s 25 Most Influential Teens. He is affiliated with research labs at Harvard and Massachusetts General Hospital.

“For me, Claisen is a continuation of everything I’ve tried to do since I was 13,” said Rishab Jain, founder & CEO of Claisen. “Whether it was helping oncologists or neuroscientists, my goal has always been to take complicated problems and translate them into something that actually helps people. Claisen is the same; Claisen is aimed at the digestive issues millions of people face every day.”

Why Rishab founded Claisen

Digestive problems are among the top drivers of healthcare visits in the US. In fact, gastrointestinal complaints account for nearly 10% of all primary-care consultations (NIH). Many patients continue to face overprescription, lack of adherence to treatment, and self-diagnosis. Aditya Jain, Claisen’s Chief Medical Officer and an MD Candidate at the Harvard School of Medicine says that “Claisen was born because people deserve better than guesswork”.

How Claisen Works
A three-minute intake quiz maps symptom patterns, triggers, and lifestyle factors such as sleep, diet, and travel. This personalises the medicines and supplements that Claisen will ship monthly to patients in the United States. This will encode an understanding of what the patient is facing: heartburn, bloating, or gas.
Users receive daily and nightly step-wise plans (meal spacing, head-of-bed elevation, fibre pacing) paired with explanations since gut health extends beyond just medication.
Lightweight check-ins help users adapt without starting over, reinforcing adherence.
From Researcher to Entrepreneur
Jain has long been recognised for bridging science and patient impact. His pancreas-tracking AI caught international media attention, while his ICOR codon-optimisation tool became a published software package in BMC Bioinformatics. With Claisen, Rishab is applying the same principle: distill scientific complexity to inform better bedside outcomes.