G protein-coupled receptors (GPCRs) constitute a large protein family of receptors that interact with molecules outside the cell and activate intracellular signal transduction pathways.
GPCR-ligand binding activates second messengers such as cAMP, inositol phosphate and calcium which regulate proteins involved in gene expression and a variety of cellular responses. GPCRs are involved in several types of disease and are the target of approximately 40% of all modern medicinal drugs.


GenScript offers a comprehensive portfolio of stable, validated GPCR cell lines for high throughput screening and compound profiling in multiple assay platforms.



Key Features:

Applicable to multiple drug targets
Ready for compound screening
Remain stable after 16 generations