Membrane protein expression remains a bottleneck in its characterization and structure determination. In a recent study, scientists created a robust strategy to increase the probability of membrane protein overexpression by generating a traceable fusion system at the C-terminus of their target protein, showing that manipulation of transcriptional silencing improved membrane protein overexpression.

For years, Genscript scientists have produced challenging membrane proteins in bacterial insect, mammalian and yeast expression systems. With its world-class expertise and PhD-level technical support, GenScript will be a reliable partner for all your protein production needs.