Traditional immunoprecipitation (IP) uses agarose beads coated in protein A/G and requires at least three washing steps to eliminate background and non-specific binding. Since each wash can result in sample loss or left-over residual contaminants, it is critical to optimize your protocol.


The use of magnetic beads is gaining popularity as a quicker, more accurate approach for immunoprecipitation. Unlike agarose, no columns or centrifugations are required. Also, you can significantly reduce experiment variability by being able to remove all of the supernatant without disturbing your pellet. You will consistently get more reliable and reproducible data with GenScript MagBeads.